Banca de DEFESA: ROUSILANDIA DE ARAUJO SILVA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : ROUSILANDIA DE ARAUJO SILVA
DATA : 30/05/2018
HORA: 14:00
LOCAL: Faculdade de Farmácia-UFBA-campus Ondina
TÍTULO:

Development of formulations for cutaneous moisturizing by cold emulsification: evaluation of sensorial properties. 

PALAVRAS-CHAVES:

Hydration, Cold Emulsification, Sensory Properties

PÁGINAS: 107
GRANDE ÁREA: Ciências da Saúde
ÁREA: Farmácia
SUBÁREA: Farmacotecnia
RESUMO:

Skin products occupy the eighth position in the ranking of the most consumed cosmetics, and moisturizers represent the most important class of this group, since they play an important role in the prevention of xerosis and skin aging. Emulsion is the most used pharmaceutical form for topical products and their preparation requires energy, time and equipment expenditures, so the cold emulsification process minimizes the costs of the production process. In this context, the present study aims to develop cold emulsified formulations with the aid of the Gelaid CPE CF ® silicon base using vegetable oils of Sweet Almond (GA), Gueroba (GGE) and Macaúba (GM) and Urea (GU) moisturizing active ingredients. Oleate Lactate (GL), Octadecila Lactate (GO) and Urea Glycospheres (GG) evaluating their sensory properties. The study was divided into three stages. The first one was the study of the Stability of the Formulations following its behavior during the 90 days by means of the macroscopic evaluation, analysis of the pH, Spreadability in vitro. All formulations remained stable without change in their organoleptic characteristics and remained within the cutaneous pH. In the group of vegetable oils the GM formulation (Eimax 3739.8mm2) presented better spreadability performance and in the group with active moisturizing the GO formulation (Eimax 2687.95 mm2). The second stage was the sensorial characterization through the determination of the texture profile and the rheological behavior. In the texture, the GGE formulation recorded lower values of firmness (4.73 g) and in the group with active the GO formulation (4.63 g). The rheological evaluation determined that all formulations presented pseudoplastic behavior with thixotropy and better recovery for GM and GO formulation in their respective groups. The last step of the study was the sensory analysis by the preference method in which the formulations with the highest score, in the case of GGE oils (44 points) and the active ones at GO (60 points) were considered preferred as regards spreadability by the research participants. The results found in the formulations with oil and moisturizing active demonstrate the feasibility in developing moisturizing products by the process of cold emulsification with different raw materials.

MEMBROS DA BANCA:
Presidente - 1211160 - NEILA DE PAULA PEREIRA
Externo ao Programa - 2765101 - ADEMIR EVANGELISTA DO VALE
Externo à Instituição - ANDRE LUIS MORAIS RUELA - UFOP