Banca de DEFESA: LUISA FLORÊNCIA CHONGO NAMBURETE

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : LUISA FLORÊNCIA CHONGO NAMBURETE
DATA : 30/06/2020
HORA: 14:00
LOCAL: NUTS – Núcleo Universitário de Telessaúde - HUPES/UFBA - Plataforma Conferência Web da RNP – O link 
TÍTULO:

 

EPIDEMIOLOGICAL FREQUENCY OF ADVERSE EVENTS FOLLOWING MEASLES AND RUBELLA IMMUNIZATION IN MOZAMBIQUE, 2018

PALAVRAS-CHAVES:

Immunization. Measles. Rubella. Adverse Events Following Immunization. Mozambique.

PÁGINAS: 70
GRANDE ÁREA: Ciências da Saúde
ÁREA: Farmácia
RESUMO:

OBJECTIVES: To analyze the epidemiological frequency of Post-Vaccination Adverse Events (PVAEs) of measles and rubella reported in the National Pharmacovigilance System in children from 6 months to 14 years old, in 2018 year in Mozambique. The specific objectives were: to identify the main PVAEs against measles and rubella in children from 6 months to 14 years old, notified in the National Pharmacovigilance System in Mozambique; compare the frequency of PVAEs by age, sex and geographic region (South, Center and North) of the country; classify PVAEs according to their severity; and to evaluate the association between the variables of interest (region of origin, sex of the child, professional category and age) and the type of PVAEs. METHODS: As for the approach, the research is quantitative. Secondary data from the Surveillance System of the National Directorate of Pharmacy of the Ministry of Health, in Mozambique, referring to PVAEs notifications for the year 2018 were analyzed. Data collection was retrospective, based on the notification forms of vaccinations made by the sentinel health units located in all provinces, based on the PVAEs notification criteria recommended by World Health Organization (WHO). The data were processed using the SPSS statistical package, version 20. In the analysis and interpretation of the results, descriptive statistics were used through tables and graphs. Hypothesis tests were also used to assess the association between the region of origin, the child's sex, professional category and age and the type of PVAEs. RESULTS: The results of the study showed that fever, body warming and vertigo are the most frequent manifestations. In addition, Tete province has a high number of serious adverse events (8%), followed by Gaza province (5%). The province of Niassa and Nampula have not been notified of any serious adverse events. For mild adverse events, they were most frequently highlighted in Sofala province with 41%, followed by Tete province with 30%, Gaza province with 25% and with less emphasis went to Maputo provinces (3%), followed by Inhambane province with 4% and lastly Maputo City. CONCLUSIONS: The results of this study confirm the importance of implementing an active surveillance system to improve the overall performance of the Pharmacovigilance system and the early detection of adverse events after immunization and to adequately quantify them and provide valuable information considered for the formulation of evidence-based policies. Post-vaccination adverse events are often mild.

MEMBROS DA BANCA:
Externo à Instituição - ANTONIO CARLOS BEISL NOBLAT - UFBA
Presidente - 096.219.544-87 - LUCIA DE ARAUJO COSTA BEISL NOBLAT - UFRN
Externo à Instituição - NEY CRISTIAN AMARAL BOA SORTE
Externo ao Programa - 2556460 - PABLO DE MOURA SANTOS