Banca de DEFESA: ANA GABRIELA PRAZERES OLIVEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : ANA GABRIELA PRAZERES OLIVEIRA
DATA : 26/08/2021
HORA: 09:00
LOCAL: Sessão Remota
TÍTULO:

COST-EFFECTIVENESS OF INHALED NITRIC OXIDE IN THE TREATMENT OF PERSISTENT PULMONARY HYPERTENSION IN THE NEWBORN

PALAVRAS-CHAVES:

Persistent Fetal Circulation Syndrome, Infant, Cost-Effectiveness Evaluation, Nitric Oxide

PÁGINAS: 69
GRANDE ÁREA: Ciências da Saúde
ÁREA: Saúde Coletiva
RESUMO:

Persistent Pulmonary Hypertension of the Newborn (PPPN or PPHRN) is a clinical syndrome characterized by severe hypoxemia, lability of oxygenation with minimal handling and generalized cyanosis, defined by the presence of high pulmonary vascular resistance and right-to-left shunt through the ductus arteriosus and/ or foramen ovale. This disease is associated with high morbidity rates, mainly due to neurological damage in 15 to 20% of cases. The treatment of this pathology must be carried out in the Neonatal Intensive Care Unit and consists of decreasing pulmonary vascular resistance in the use of pulmonary vasodilators, the gold standard treatment being the use of inhaled nitric oxide (iNO), which has a high cost and the possibility of therapeutic failure. The aim of this study was to analyze the cost-effectiveness of using inhaled nitric oxide in the treatment of PPHN compared to standard care offered by SUS. A cost-effectiveness evaluation (ACE) was carried out in a decision tree analytical model, based on secondary data, and with the help of the statistical program TreeAge Pro Healthcare, the calculation of the incremental cost-effectiveness ratio was performed. When calculating the ICER, treatment with iNO had a cost of R$13,585.47 per life saved and a cost of R$240.50 per potential life years gained compared to treatment without iNO. The results obtained demonstrate that nitric oxide therapy in neonates is more cost-effective.

MEMBROS DA BANCA:
Externo à Instituição - IVAN RICARDO ZIMMERMANN - UnB
Externo à Instituição - CAROLINA THÉ MACEDO - UFBA
Presidente - 701.890.055-72 - FABIANA RAYNAL FLORIANO - MS