Banca de DEFESA: THIAGO RHANGEL GOMES TEIXEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : THIAGO RHANGEL GOMES TEIXEIRA
DATA : 21/12/2020
HORA: 16:00
LOCAL: Remotamente
TÍTULO:

COMPARATIVE STUDY BETWEEN TREATMENT EXPENSES OF SHOULDER OSTEONECROSIS IN PATIENTS WITH ANEMIA FALCIFORM, WITH THE USE OF STEM CELLS AND TOTAL ARTHROPLASTY

PALAVRAS-CHAVES:

Spending assessment; stem cells; Shoulder Arthroplasty; Sickle Cell Anemia

PÁGINAS: 39
GRANDE ÁREA: Ciências da Saúde
ÁREA: Saúde Coletiva
RESUMO:

The general objective of the research is to compare the costs of treating osteonecrosis of the shoulder in patients with sickle cell anemia treated with the use of bone marrow mesenchymal cells and patients treated in the conventional manner (arthroplasty) at the Professor Edgar University Hospital Complex. Santos (COM - HUPES) and, as specific objectives, describe clinical characteristics such as onset of symptoms, lesion laterality, location of osteonecrosis and restrictions on activities of daily living. Sickle cell disease is a public health problem, especially in the state of Bahia, due to its high prevalence, and for causing serious complications to the individual's health. Therefore, the need for research on less invasive, costly and better recovery treatment is justified. The use of the autologous CMMO implant appears as a new alternative, with good results and greater comfort and safety. What shows the importance of this study to analyze the advantages of the proposed treatment, in comparison to the conventional one (use of prostheses), so that we realize the difference in costs, length of hospital stay, recovery time and return to activities. The methodological framework is based on a retrospective cohort study, focusing on expenditures made with patients with SCD and followed up, over a period of 14 years, between 2005 and 2019, at Com-HUPES, with the selection of the population of the study, was performed by analyzing medical records and patient records, with osteonecrosis of the shoulder. Thus, we evaluated the cost of surgery for cell therapy by analyzing the data from the Com-HUPES cell therapy treatment project compared to the SUS table of values for the total shoulder arthroplasty procedure, which is still the standard treatment. - recommended gold. We analyzed the surgical / clinical data of 29 people diagnosed with sickle cell disease and with osteonecrosis, of both sexes, aged between 18 and 42 years. The results obtained show that the costs of surgery in which the humeral head is replaced with the use of prostheses (total of R $ 4,121.52), have a cost of at least R $ 965.85 (23.43%) more than surgery with the implantation of stem cells (total of R $ 3,155.67). We can conclude, in this way, that in addition to the indisputable advantage for the patient - such as shorter hospital stay (which indirectly brings numerous benefits, such as lower risk of infections, embolism, thrombi, etc.), better recovery, return to the daily activities of earlier, less local aggression and consequently less painful process, among other countless benefits - there is also an evident savings for public coffers and for the Unified Health System, where we realize savings of approximately 25% of the costs with the procedure using the stem cells in relation to conventional treatment with shoulder arthroplasty.

MEMBROS DA BANCA:
Externo à Instituição - ADEMARIO GALVAO SPINOLA - UFBA
Presidente - 286128 - GILDASIO DE CERQUEIRA DALTRO
Externo à Instituição - JANE MARY DE MEDEIROS GUIMARÃES - UFSB
Externo ao Programa - 286053 - MARIO CASTRO CARREIRO