Epidemiological and clinical characteristics of COVID-19 in a Brazilian public hospital
COVID-19; coronavirus; symptoms; virus SARS-CoV-2, UTI
The Coronavirus disease 2019 (COVID-19) pandemic has become a major health concern worldwide. In that context, the understanding of epidemiological and clinical features associated with the disease and its severity is crucial for the establishment of strategies aiming at disease control. This study aims to describe epidemiological features, signs, symptoms, and laboratory findings among severely ill COVID-19 patients from an intensive care unit in Northeastern Brazil as well as to evaluate predictor factors for disease outcomes. The study included 115 hospitalized COVID-19 patients, with a median age of 65.60 ± 15.78. Dyspnea was the most frequent symptom, affecting 73.9% of the patients, followed by cough (54.7%). Fever was reported in approximately one third and myalgia in 20.8% of the patients. At least two comorbidities have been found in 41.7% of the patients, and hypertension was the most prevalent one (57.3%). In addition, having two or more comorbidities was a predictor of mortality, and lower platelets count was positively associated with death as well. Regarding symptoms, nausea and vomiting were predictors of death and cough was a protective factor. Some differences in the clinical and epidemiological features in COVID-19 patients were found in this study when compared to previous investigations. This is the first report of a negative correlation between cough and death in severely ill SARS-CoV-2-infected individuals.