Banca de DEFESA: MARTA MARIA SILVA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : MARTA MARIA SILVA
DATA : 28/05/2021
HORA: 14:00
LOCAL: videoconferência RNP
TÍTULO:

"Prevalence and distribution of serotypes of Streptococcus agalactiae isolated in pregnant women in the municipality of Vitória da Conquista-BA"

PALAVRAS-CHAVES:

Streptococcus agalactiae, virulence, serotype, PCR.

 

PÁGINAS: 78
GRANDE ÁREA: Ciências Biológicas
ÁREA: Microbiologia
SUBÁREA: Microbiologia Aplicada
ESPECIALIDADE: Microbiologia Médica
RESUMO:

Streptococcus agalactiae or group B streptococci (GBS), are Gram positive, catalase and oxidase negative bacteria in the form of cocci, arranged predominantly in chains. They reside commensally in the gastrointestinal and genitourinary tracts of humans, with the potential to trigger serious infections. In neonates, it is one of the most relevant causes of morbidity and mortality. The manifestations of the disease can vary between sepsis, pneumonia and meningitis. The capsular polysaccharide represents the most relevant virulence factor and determines the classification of the 10 serotypes already described. The present paper is an excerpt of a larger study, with the objective of disclosing the prevalence of serotypes of 34 strains of Streptococcus agalactiae isolated from colonized pregnant women in the county of Vitória da Conquista - BA. Molecular serotyping techniques were used, via multiplex PCR and gel electrophoresis. Serotype Ia was the most prevalent 44.11% (15/34), followed by serotypes Ib, 26.47% (9/34) and II, 8.82%, (3/34). Serotype IX was the least prevalent 2.94%, (1/34). Non-typable strains represented 17.64% (6/34) of the sample. This study presented the first data on the distribution and prevalence of GBS serotypes in the county, which strengthens the data already found on the prevalence of colonization in pregnant women and their sensitivity profile. These results also significantly assist local managers in making decisions to implement actions that reduce the vertical transmission of this microorganism, further corroborating to the reduction of impacts on the health and economy of the county.

 

MEMBROS DA BANCA:
Presidente - 1739574 - MARCIO VASCONCELOS OLIVEIRA
Interno(a) - 2315391 - FABRICIO FREIRE DE MELO
Externo(a) ao Programa - 3224857 - CLAUDIO LIMA SOUZA