Banca de DEFESA: JULIANA COSTA SANTOS
Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.DISCENTE : JULIANA COSTA SANTOS
DATA : 08/12/2020
HORA: 09:00
LOCAL: PLATAFORMA GOOGLE MEET
TÍTULO:
Neuropsychomotor Development and Functional Skills of Children with Chronic Liver Diseases.
PALAVRAS-CHAVES:
Child Development. End Stage Liver Disease. Development of disabilities. Perception.
PÁGINAS: 121
GRANDE ÁREA: Ciências da Saúde
ÁREA: Fisioterapia e Terapia Ocupacional
RESUMO:
To systematically review and evaluate by meta-analysis the effects of liver disease on the neuropsychomotor development of children and adolescents with their native livers (FN) and those who underwent liver transplantation (TxH) - article 1. Assess neuropsychomotor development (DNPM) and relate to the appropriate skills of children with chronic liver diseases from 0 to 6 years old (article 2). Describe the necessary skills of children and adolescents with liver disease (article 3). And to report the perception of mothers of children with liver disease about the DNPM, relating it to the results of the Denver II Screening Test - TTDII (article 4). Methods: Descriptive exploratory, sectional study, with a quantitative and qualitative approach, in which 73 children and adolescents from six months to seventeen years with chronic liver diseases attended at a Reference Center in the state of Bahia and their main caregivers from November 2018 to March 2020. In article 1, searches were carried out in the PubMed databases and Scopus journals from the first publications in the 1980s until June 2019, for observational studies. TTDII was evaluated in 32 children and after carrying out informing parents Inventory of Pediatric Disability Assessment (PEDI-CAT) in article 2. In article 3, the quick version of PEDI-CAT was applied to the expanded sample with 73 parents of children aged 0 to 17 years. The domains are daily activity, mobility, social cognitive and responsibility. In article 3, a narrative interview was conducted with the following triggering question: “What do you think of your child's development?” an interview was recorded and the data was transcribed. Results: In article 1, 25 studies were included with 909 children and adolescents with liver disease. Meta-analyzes increase total deficits IQ -0.41 (95% CI: -0.51 to -0.32; N: 9.973), verbal IQ - 0.38 (CI: 95%; - 0.57 to -0, 18; N: 10,284) and receptive language - 0.85 (CI: 95%; - 1.16 to - 0.53; N: 921) in TxH. In those with FN that were associated early, their Total and Verbal IQ scores (85 ± 8.8; 86.3 ± 10.6 respectively) were lower than those with late clinical manifestations (99.5 ± 13.8; 96.2 ± 9.2). In article 2, it was observed that in TTDII, 71.9% (23/32) of the sample showed suspicion / risk for DNPM. The relationship between the TTDII and PEDI-CAT instruments, it was found that among children with liver disease suspected / at risk for DNPM, the normative score / T-Score was 60.74 ± 9.18 for daily activities, 57.61± 11.84 for the mobility domain and 48.35 ± 6.29 for the social / cognitive domain. In article 2, the normative scores / T-Scores of activities of daily living with FN was 56.30 ± 10.67, mobility 49.09 ± 16.76 and the socio / cognitive score 44.46 ± 11, 02, responsibility 49.84 ± 11.87. Those who were transplanted obtained results from activities of daily living 51.20 ± 7.34, mobility 38.13 ± 19.99 followed by socio / cognitive scores 42.87 ± 10.59 and responsibility 49.83 ± 10.88. The mothers' perception of their children's development coincided with the results of the TTDII. Conclusion: Acute or chronic liver disease can cause declines in cognitive, motor and language functions. When assessed by the TTDII, children with liver disease dissipate the potential risk for delays in the DNPM, however, these skills have not dissipated by PEDI-CAT, even when the expanded sample has been expanded to older children and adolescents. The mothers of children with liver disease, in general, demonstrated a good perception about their children's DNPM, that is, these mothers can identify typical and atypical characteristics.
MEMBROS DA BANCA:
Interno - 1866030 - HELENA FRANCA CORREIA
Presidente - 104.946.855-49 - LUCIANA RODRIGUES SILVA - UFBA
Externo à Instituição - MAÍRA FERREIRA DO AMARAL - UFTM
Externo ao Programa - 2091250 - MICHELI BERNARDONE SAQUETTO
Externo à Instituição - VITOR OLIVEIRA CARVALHO - UFS