Banca de DEFESA: ANA PAULA AZEVEDO MACEDO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : ANA PAULA AZEVEDO MACEDO
DATA : 20/08/2020
HORA: 14:00
LOCAL: Salvador
TÍTULO:

EFFECT OF REGULAR GREEN TEA CONSUMPTION ON METABOLIC CHANGES INDUCED BY A HYPERLIPID DIET IN MICE

PALAVRAS-CHAVES:

Camellia sinennis, obesity, adipose tissue, blood glucose and insulin

PÁGINAS: 73
GRANDE ÁREA: Ciências da Saúde
ÁREA: Nutrição
SUBÁREA: Bioquímica da Nutrição
RESUMO:

Obesity is a complex disorder associated with adverse health consequences, including dyslipidemia, high blood pressure, type 2 diabetes, and non-alcoholic liver steatosis. As this disease is increasing, more and more alternative treatments such as herbal medicines are being sought, due to the low cost and easy access, mainly through the consumption of teas. The objective of this study was to evaluate the effect of a green tea (Camellia sinensis) infusion regular consumption on metabolic changes in mice and the use of a high-fat diet. The C57 / BL6 mice were segregated into four groups: control diet plus autoclaved water or green tea and high-fat diet plus autoclaved water or green tea for 16 weeks. Weight and waist circumference were measured every two weeks and blood glucose was measured every four weeks of experience. Oral glucose and insulin tolerance tests were performed in the last week. In the sixteenth week, after the animal was euthanized, the adipose tissue was dissected and weighed. The consumption of green tea in mice fed a high-fat diet promoted a weight reduction in the sixth and sixteenth weeks (p <0.01), a significant reduction in waist circumference in the fourth week (p <0.05) and continuously from the eighth week (p <0.05; p <0.01). The infusion of green tea reduced the deposition of adipose tissue in all analyzed compartments (p <0.001), including brown adipose tissue (p <0.01). Fasting blood glucose showed a significant reduction only in the sixteenth week (p <0.05) and the peak of blood glucose in the 15-minute time of the oral glucose tolerance test (p <0.01) showed a significant reduction for the high-fat group that consumed green tea. In conclusion, green tea promoted a reduction in weight and waist circumference, as well as the deposition of adipose tissue in all compartments analyzed in C57/BL6 mice submitted to the consumption of a high-fat diet

MEMBROS DA BANCA:
Externo à Instituição - JAILANE DE SOUZA AQUINO
Interno - 3053917 - KARINA TEIXEIRA MAGALHAES GUEDES
Presidente - 1490663 - RICARDO DAVID COUTO