Banca de DEFESA: RAMON RODRIGUES SÁ

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : RAMON RODRIGUES SÁ
DATA : 19/06/2020
HORA: 08:30
LOCAL: Plataforma Conferência Web da RNP
TÍTULO:

 

Bioprospecting of plant assets for application as excipients oral solid pharmaceutical forms

PALAVRAS-CHAVES:

Starch; Phenolic Compounds; Plant Extract; Tablet.

PÁGINAS: 100
GRANDE ÁREA: Outra
ÁREA: Tecnologia e Inovação
RESUMO:

Bioprospecting consists of the identification and evaluation of biological material found in nature, to obtain new products or processes. Industrial interest in the use of natural products in pharmaceutical formulations has increasingly increased. Currently, several studies are focused on plant extracts, but tropical fruits such as jambo and jabuticaba remain little explored and, consequently, underutilized.  This research aims to investigate plant derivatives with applications such as excipients in oral solid pharmaceutical forms. The fruits and extracts of Syzygium malaccense (jambo) and Plinia cauliflora (jabuticaba) were evaluated, aiming at the development of an oral solid pharmaceutical form from the plant derivatives obtained from the analyzed fruits, in order to stimulate the tropical fruit research and encourage regional economic development. The centesimal composition increased a high concentration of carbohydrates, results that boosted starch research in both fruits. Phytochemical screening has increased the presence of flavonoids and polyphenols, being a favorable condition for antioxidant activity research. Both fruits presented the presence of starch, and jambo was the fruit with the highest concentration. The extracts of both fruits present high concentrations of phenolic compounds and positive antioxidant activity.  The use of these plant derivatives may favor the reduction of the concentration of synthetic excipients in the composition of the drug, reducing the toxicity associated with various compounds. The production of medicines using an unconventional starch, such as jambo, will be of great importance for the pharmaceutical industrial sector, and can reduce the cost of production, considering the great biodiversity existing in the country, representing a large scientific and economic impact.

MEMBROS DA BANCA:
Presidente - 2765101 - ADEMIR EVANGELISTA DO VALE
Externo à Instituição - DÉBORA DE ANDRADE SANTANA
Externo à Instituição - LUCAS GUIMARÃES CARDOSO