Banca de DEFESA: AYSLANY MELO RODRIGUES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : AYSLANY MELO RODRIGUES
DATA : 28/03/2019
HORA: 14:30
LOCAL: Auditório da Congregação, 2º andar, Instituto de Ciências da Saúde, UFBA.
TÍTULO:

STUDY OF GENOTYPES AND VARIABILITY OF THE CHIKUNGUNYA VIRUS (CHIKV) IN THE SANTANA, SALVADOR AND METROPOLITAN REGION FAIR FOR THE PERIOD 2014 TO 2018

PALAVRAS-CHAVES:

Chikungunya. Virus. ECSA. Genotyping. Surveillance

PÁGINAS: 100
GRANDE ÁREA: Outra
ÁREA: Tecnologia e Inovação
RESUMO:

Chikungunya fever is an arbovirose whose etiological agent, Chikungunya virus (CHIKV) was first identified in 1952 in Tanzania. Since then the virus has caused epidemics and neuro-motor complications worldwide, with mosquitoes of the genus Aedes as vectors responsible for transmitting the disease.

CHIKV has four lineages currently described: ECSA (East-Central-South African), WA (West African), Asian and IOL (Indian Ocean Lineage). In Brazil, the first infection occurred in 2014, in the states of Amapá and Bahia, and two circulating strains, Asian and ECSA, respectively, were identified.

The quick expansion of CHIKV in the Americas, especially with the outbreak in Brazil in 2015, has attracted the attention of authorities and researchers. In order to provide information to the surveillance of CHIKV circulating strains, the present work aimed to isolate viral strains of serum samples from infected patients in the state of Bahia, Brazil, between 2014 and 2018, and to genetically characterize the circulating genotype in the region.

Throughout genotyping by phylogenetic grouping of maximum likelihood, it was possible to conclude that the isolated strains are of ECSA lineage. It was also possible to report the efficiency of the genotypic characterization from a small fragment of cDNA, containing 305 base pairs from an E2 protein region, and so increasing the possibilities for the genotypic characterization of CHIKV.

MEMBROS DA BANCA:
Externo à Instituição - DELLANE MARTINS TIGRE - UESB
Presidente - 090.842.665-87 - GUBIO SOARES CAMPOS - UAM
Interno - 287168 - LILIA FERREIRA DE MOURA COSTA
Interno - 6285947 - ROBERTO JOSE MEYER NASCIMENTO