Banca de DEFESA: HELLEN BOLZANNI

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : HELLEN BOLZANNI
DATA : 19/03/2020
HORA: 14:00
LOCAL: Sala 106 / STI / UFBA
TÍTULO:

Quantitative evaluation of tears, nasolacrimal stimulation and test-retest repeatability in brachycephalic and non-brachycephalic dogs.

PALAVRAS-CHAVES:

canine, corneal sensitivity, nasolacrimal reflex, tear production

PÁGINAS: 80
GRANDE ÁREA: Ciências Agrárias
ÁREA: Medicina Veterinária
RESUMO:

Ocular surface disorders or aqueous tear deficiency are conditions commonly diagnosed in veterinary practice, especially in dogs. Thus, the aim of this study was to characterize diagnostic findings, test-retest repeatability, and correlations among lacrimal tests in dogs of diverse cephalic conformations. The study population comprised 50 clinically healthy dogs (25 brachycephalic and 25 non-brachycephalic). A series of diagnostics were performed in each dog, allowing for a 10min-interval between tests and repeating each test 24h later under similar conditions: corneal tactile sensation (CTS), strip meniscometry test (SMT), phenol red thread test (PRTT), endodontic absorbent paper point tear test (EAPPTT), Schirmer tear test-1 without (STT-1) or with nasolacrimal stimulation (NL-STT-1), and Schirmer tear test-2 (STT-2). Mean ± SD test values were lower in brachycephalic vs. non-brachycephalic dogs (except for SMT; 7.4 ± 2.0 vs. 7.3 ± 2.4 mm/5s without significant difference), with statistically significant differences noted for CTS (1.8 ± 0.5 cm vs. 3.4 ± 0.8 cm), PRTT (37.2 ± 4.0 mm/15s vs. 41.1 ± 5.5 mm/15s), STT-1 (20.1 ± 3.4 mm/min vs. 23.3 ± 5.7 mm/min) and NL-STT1 (23.2 ± 3.6 mm/min vs. 27.1 ± 5.4 mm/min), and non-significant differences for EAPPTT (16.6 ± 2.7 mm/15s vs. 17.5 ± 2.9 mm/15s). Nasolacrimal stimulation increased STT-1 values by 18% on average. Correlations among tests were generally weak to moderate (r < 0.70) except for a strong positive correlation between STT-1 and NL-STT1 (r= 0.83, P < 0.001). Tests reliability was good although test-retest repeatability was generally poor to moderate, as depicted by low intraclass correlation coefficients (ICC ≤ 0.75) and wide 95% limits of agreement, except for CTS (ICC = 0.91). In fact corneal sensitivity and aqueous tear secretion are lower in brachycephalic dogs. A comprehensive assessment of the ocular surface requires the combination of several diagnostic tests. The nasolacrimal reflex may provide a useful diagnostic and therapeutic tool in dogs.

MEMBROS DA BANCA:
Presidente - 1675087 - ARIANNE PONTES ORIA
Externo à Instituição - EMANOEL FERREIRA MARTINS FILHO - UFBA
Externo à Instituição - MARCELA ALDROVANI RODRIGUES
Externo ao Programa - 287212 - THEREZA CRISTINA BORIO DOS SANTOS CALMON DE BITTENCOURT