RISK OF MALNUTRITION AND CLINICAL EVOLUTION IN PATIENTS HOSPITALIZED FOR COVID-19 IN NORTHEASTERN BRAZIL: A MULTI-CENTRIC STUDY
COVID-19; Weight loss; Appetite; Hospitalization; Mechanical ventilation; Mortalit
The risk of malnutrition in patients with the new coronavirus disease has been associated with worse outcomes, including mortality. Impaired nutritional status can impair the effectiveness of treatments, which may be related to increased morbidity and mortality. The aim of the study is to evaluate the association between the risk of malnutrition and the clinical evolution of hospitalized patients with COVID-19. Methods: This is a multicentric cohort, carried out in the Northeast of Brazil. Sociodemographic, clinical, and nutritional data were collected on hospitalized patients diagnosed with COVID-19. The risk of malnutrition will be assessed using the Malnutrition Universal Screening Tool (MUST). Clinical outcomes included admission to the intensive care unit or medical clinic, type of ventilation (spontaneous ventilation or mechanical ventilation), discharge and death. Results: 459 patients were included, most of them adults (64.5%), male. According to the MUST tool, 84.5% of patients were at moderate or high nutritional risk, such patients had a higher prevalence of involuntary weight loss and loss of appetite, compared to the group of patients with low risk of malnutrition (47.2 % vs 14.1%) and (71.9% vs 1.4%), (p<0.05), respectively. In addition, the presence of high nutritional risk was associated with worse clinical outcomes, such as admission to the intensive care unit, use of mechanical ventilation and mortality (49.7% vs 0.0%), (39.7% vs. 0.0%) and (25.5% vs 4.2%), (p<0.05), respectively. Conclusion: The nutritional status of patients with COVID-19 is closely related to clinical outcomes. The use of nutritional screening tools is the first step in the nutritional care of hospitalized patients, which can lead to better results, especially in patients at high nutritional risk