Banca de DEFESA: ARLINDA SANTOS SEIXAS ROSA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : ARLINDA SANTOS SEIXAS ROSA
DATA : 10/06/2021
HORA: 09:00
LOCAL: https://conferenciaweb.rnp.br/webconf/jairza-maria-barreto-medeiros
TÍTULO:

Association between Maternal Anthropometric Nutritional Status and Occurrence of Congenital Microcephaly by Zika Virus

PALAVRAS-CHAVES:

Zika Virus, Congenital Microcephaly, Pre-gestational Body Mass Index (BMI), Gestational Weight Gain, Risk Factors.

PÁGINAS: 66
GRANDE ÁREA: Ciências da Saúde
ÁREA: Nutrição
SUBÁREA: Análise Nutricional de População
RESUMO:

Brazil was the first country to investigate the relationship between congenital Zika virus (ZIKV) infection and microcephaly. The potential risk of ZIKV infection during pregnancy to cause microcephaly is poorly understood. Genetic predisposition and environmental factors are possible cofactors that can increase susceptibility to ZIKV infection and lead to phenotypic changes in the brain. Several factors have been proposed to influence the fetal outcome during maternal ZIKV infection; however, the effect of maternal anthropometric nutritional status has not been investigated. Maternal anthropometric nutritional status, estimated by pre-gestational maternal body mass index (BMI) and gestational weight gain, has been widely studied as a predictor of adverse pregnancy outcomes, including spontaneous abortion, premature birth, low birth weight and congenital anomalies. Objective: To investigate possible associations between maternal anthropometric nutritional status before and during pregnancy and the occurrence of microcephaly due to ZIKV infection. Methodology: This is a cross-sectional study, with a sample consisting of 121 mothers with exposure to ZIKV during pregnancy confirmed by the Neutralization Test by Plaque Reduction (PRNT). The mothers were divided into two groups: with and without microcephaly in newborns. Results: Most women with microcephalic children (n = 35) were young <30 years of age (82.4%), black (93.9%), with unsatisfactory self-reported family income (70%), primiparous (57.1%), with cesarean delivery (55.9%) and inadequate weight gain (60%). Family income was associated with microcephaly (p = 0.035). And mothers with low weight at the beginning of pregnancy were more likely to have children with microcephaly (adjusted OR = 11.72; 95% CI: 1.15 - 119.11). Conclusion: Maternal anthropometric nutritional status may have an influence on the occurrence of microcephaly due to congenital ZIKV infection. Low pre-pregnancy weight was associated with cases of microcephaly. And a higher prevalence of microcephaly found among mothers with insufficient weight gain during pregnancy.

MEMBROS DA BANCA:
Presidente - 1066101 - JAIRZA MARIA BARRETO MEDEIROS
Interno(a) - 1194475 - MONICA LEILA PORTELA DE SANTANA
Externo(a) à Instituição - WYLLA TATIANA FERREIRA E SILVA