Banca de DEFESA: ELLAYNE SOUZA CERQUEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : ELLAYNE SOUZA CERQUEIRA
DATE: 06/11/2023
TIME: 15:00
LOCAL: Auditório Professora Ana Marlúcia Oliveira, Enufba
TITLE:

OROPHARYNGEAL IMMUNOTHERAPY OF COLOSTRUM AND WEIGHT GAIN IN PREMATURE VERY LOW WEIGHT NEWBORN


KEY WORDS:

Premature newborn,Very low birth weight newborn, Colostrum, Immunotherapy, Body weight, Weight gain


PAGES: 68
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:
Oropharyngeal ColostrumImmunotherapy (IOC) assists inthe initiation and progression
ofnutritionaltherapybypromotingintestinalgrowthandmaturation,reducingfood
intoleranceeventsandimprovingtheclinicalevolutionofprematurenewborns.However,
the result of this immunotherapy on weight gain in neonates has been little explored. For
thisreason,thepresentstudyevaluatedtheeffectoforopharyngealcolostrum
immunotherapyonthegrowthvelocityofverylowbirthweightprematurenewborns
admitted to a public maternal and child care unit.
Thisisanon-randomizedclinicaltrialwithhistorical control.Premature newbornsborn
weighing less than 1500g were allocated into two groups according to the period of their
admissiontotheneonatalintensivecareunit:inthecontrolgroup,thoseadmittedbetween
2015and2018,andintheinterventiongroup,thoseadmittedaftertheimplantationofa
IOCprotocol,between2019and2020.Thetreatmentregimenconsisteddailyof8
administrationsof0.2ml(fourdrops)ofcolostrumfor10secondsintheoropharyngeal
mucosa,offered every 03hours,until theseventh dayoflifeof thechild.Newbornswere
weighednaked,onceaday,bytheteamofprofessionalsfromthesectorsinvolved,
previouslytrainedbytheresearchgroup,untilhospitaldischargeordeath.Datacollection
forthehistoricalcontrolgroupwascarriedoutretrospectivelythroughmedicalrecords.
ToassesstheeffectoftheIOContheweightgainofprematurechildren,Generalized
Estimation Equation (GEE) modeling was performed.
Intheneonatalperiod,growthdecelerationwasidentifiedinthefirst7daysoflifeinboth
groups, followedby a greaterincrease inweight gain between 21 and28 days inthe IOC
group (Pre-IOC: mean: 11.79; SD: 10.24 ; IOC: mean: 16.29; SD: 11.72; p=0.05). In the
multivariateanalysis,afteradjustingforconfoundingfactors,IOCincreasedtherateof
weight gainby1.99g/kg/day(p<0.01) andz-score forageby 0.33(p<0 ,01). Datafrom
thepresentstudysuggestthatIOCfavoredweightgaininverylowbirthweightpremature newborns in the neonatal period.

COMMITTEE MEMBERS:
Presidente - 2615563 - PRISCILA RIBAS DE FARIAS COSTA
Externa à Instituição - TATIANA DE OLIVEIRA VIEIRA - UEFS
Externa à Instituição - NAIÁ ORTELAN - Fiocruz-Ba
Notícia cadastrada em: 03/11/2023 11:26
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