NEUROPATHIC PAIN IN RHEUMATOID ARTHRITIS
Rheumatoid Arthritis. Chronic pain. Epidemiology.
BACKGROUND: Although little known, neuropathic pain (NP) in rheumatoid arthritis (RA) is a phenomenon present in a portion of patients. Knowing the DN profile in a patient with RA is fundamental for its treatment. OBJECTIVES: To characterize NP in RA patients and to investigate the independent factors associated with NP in RA, considering sociodemographic, behavioral, lifestyle, and clinical aspects (degree of deformity and level of inflammation in functional hand joints in RA individuals), in a self-reported African descent ethnicity sample. METHOD: A literature review and two cross-sectional studies. RESULTS: a literature review chapter “Neuropathic Pain in RA” and two original articles - Article 1 “Inflammation and deformity and its relation to the type of pain in rheumatoid hands: cross sectional study” and article 2 “Neuropathic pain in rheumatoid arthritis and its association with Afro-Descendant ethinicity: a hierarchical analysis “. FINAL CONSIDERATIONS: The continuous flow of new knowledge about non-inflammatory pain in RA has expanded the limits of understanding pain in this disease. The articles published in this study showed that: 1) the wrist is the joint most affected by nociceptive pain, that small deformities are associated with NP, while high degrees of deformity are more frequent in nociceptive pain; 2) NP in a sample with RA was related to self-referenced Afrodescendant ethnicity and associated with functionality and a high level of anxiety