Banca de DEFESA: TAMARA VIEIRA REIS

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : TAMARA VIEIRA REIS
DATE: 20/05/2022
TIME: 14:00
LOCAL: Instituto de Química
TITLE:

Secondary metabolites of the ethyl acetate extract of the roots of Kielmeyera reticulata

KEY WORDS:

Kielmeyera reticulata (Calophyllaceae), phloroglucinol derivative, biphenyl.

PAGES: 124
BIG AREA: Ciências Exatas e da Terra
AREA: Química
SUBÁREA: Química Orgânica
SPECIALTY: Química dos Produtos Naturais
SUMMARY:

This study describes the isolation and structural identification of secondary metabolites present on the extract in ethyl acetate obtained from the roots of the Kielmeyera reticulata Mart. (Calophyllaceae) species, collected in the sandbanks of the Parque Metropolitano do Abaeté, Salvador-Bahia. Species in this family are primarily known as sources of xanthones, which are considered their chemosystematics markers. The roots were subjected to extraction with ethyl acetate. The fractionation of the extract was carried out by vacuum flash silica column chromatography, dry packed, with the solid sample inserted, using hexane and dichloromethane in increasing order of polarity as eluent system, and the compounds were isolated by preparative chromatography on silica gel using hexane and ethyl ether as an eluting system. Compound identification was performed using spectroscopic methods such as one-dimensional (¹H and ¹³C) and two-dimensional Nuclear Magnetic Resonance (gHMBC and gHSQC). The following compounds were isolated and identified from the extract: three phloroglucinol derivatives, three biphenyls, one 4-alkylcoumarin, one xanthone and the steroids β-sitosterol and stigmasterol. Three new substances were isolated and identified: a prenylated derivative of phloroglucinol and two biphenyls.

BANKING MEMBERS:
Presidente - 1756798 - ELISANGELA FABIANA BOFFO
Interno - 3768242 - PAULO ROBERTO RIBEIRO DE JESUS
Interna - 2454639 - CALINE GOMES FERRAZ
Externo à Instituição - VLADIMIR CONSTANTINO GOMES HELENO
Externo à Instituição - WALMIR SILVA GARCEZ - UFMS
Externa à Instituição - ERIKA MARIA DE OLIVEIRA RIBEIRO - UNEB
Externa à Instituição - LOURDES CARDOSO DE SOUZA NETA - UNEB
Externa à Instituição - ANGELICA MARIA LUCCHESE