Banca de DEFESA: RAFAEL LARANJEIRA CERQUEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : RAFAEL LARANJEIRA CERQUEIRA
DATE: 15/06/2023
TIME: 19:00
LOCAL: https://us06web.zoom.us/j/89033431188?pwd=VSsva1F0aEJFdnJndHE4eTh3VzBIdz09
TITLE:

DISEASE BURDEN FOR DIABETES MELLITUS-RELATED COMORBIDITIES IN BAHIA IN 2018

KEY WORDS:

Burden of Disease, Diabetes Mellitus, comorbidities, population attributable fraction, disability-adjusted life years.

PAGES: 34
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Introduction: The relevance of studying the burden of disease for comorbidities related to Diabetes Mellitus (DM) lies in the high costs to patients, their families and the health system, since its chronic microvascular complications (chronic kidney disease, neuropathy, retinopathy and diabetic foot) negatively affect the quality of life, cause early mortality, besides generating absenteeism from work. Objective: to estimate the Burden of Disease for Diabetes Mellitus-related comorbidities in Bahia, using as indicator the Disability Adjusted Life Years (DALY) and the respective Population Attributable Fraction applied on hospital admissions in the Unified Health System (SUS) in Bahia in 2018. Methodology: This is an analytical population-based epidemiological study from the perspective of the Unified Health System (SUS), from the microdata of the Hospital Information System (SIH/SUS), in the state of Bahia, Brazil, in the year 2018. For this, the population attributable fraction (PAF) and the indicator disability-adjusted life years (DALY) were calculated, according to the most recent methodology of Global Burden of Disease studies. The burden of comorbidities was obtained by the product between the previously calculated FAP and DALY. Results: For DM chronic kidney disease, a FAP of 32.51% was found; regarding diabetic neuropathy, the analysis in different scenarios showed that having diabetes increases up to 75.7 times the chance of developing this complication; regarding diabetic retinopathy, a similar variation was found, with the FAP obtained in 1.14%. The total DALYs were 44.9 per thousand inhabitants, of which 66.04% referred to the morbidity component and 33.96% to premature deaths. With respect to sex, both men and women had the morbidity component with the greatest contribution to DM burden. However, for the age groups up to 44 years, the mortality component has greater weight, a situation that is reversed after 45 years. Women record a greater absolute number of YLL and YLD (7,030.4 and 13,448.2, respectively) than men (5,640.5 YLL and 11,188.2 YLD). However, when rates are checked, males outnumber females, with the former showing a rate of 51.91 DALY per thousand inhabitants, against 40.55 DALY per thousand for the latter group. Regarding the burden of comorbidities, for diabetes chronic kidney disease, 12. 131.3 DALY, at a rate of 14.6 DALY per thousand inhabitants, with men obtaining 16.9 DALY per thousand and women 13.2 DALY per thousand inhabitants; diabetic neuropathy showed a total of 139.8 DALY, with a rate of 0.17 DALY per thousand inhabitants, of which 76.7 DALY referred to women (0.15 DALY per thousand inhabitants) and 63.1 were attributed to men (0.19 DALY per thousand inhabitants). For the DR, 426 DALYs were observed in total, with a rate of 0.51 DALY per thousand inhabitants, of which women had 233.9 DALYs (0.46 DALYs per thousand inhabitants) and men had 192.2 DALYs (0.59 DALYs per thousand inhabitants). Conclusions: As analyzed, having DM is a high risk factor for developing related chronic microvascular complications. Among the inpatient population, a higher burden for morbidity and mortality was noted among men when compared to women, indicating the need to plan interventions and prevention policies aimed at this segment of the population.

COMMITTEE MEMBERS:
Presidente - 2425791 - ERIKA SANTOS DE ARAGAO
Externo à Instituição - GUSTAVO NUNES DE OLIVEIRA COSTA - UNIFACS
Interno - 1323871 - MARCIO SANTOS DA NATIVIDADE